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Effects of narcotic analgesics on the uptake and release of 5-hydroxytryptamine in rat synaptosomal preparations
1 The effects of various narcotic analgesics on the uptake and release of labelled 5-hydroxytryptamine (5-HT) in brain and spinal cord synaptosomes were investigated. 2 Methadone was most active in inhibiting 5-HT uptake (IC(50) 2.5 × 10(-7) M). Levorphanol also inhibited 5-HT uptake to a large exte...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1978
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1668261/ https://ncbi.nlm.nih.gov/pubmed/29686 |
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