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Modulation of 5-hydroxytryptamine efflux from rat cortical synaptosomes by opioids and nociceptin

1. The modulation of [(3)H]-5-hydroxytryptamine ([(3)H]-5-HT) efflux from superfused rat cortical synaptosomes by delta, kappa, mu and ORL(1) opioid receptor agonists and antagonists was studied. 2. Spontaneous [(3)H]-5-HT efflux was reduced (20% inhibition) by either 0.5 μM tetrodotoxin or Ca(2+)-o...

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Detalhes bibliográficos
Main Authors: Sbrenna, S, Marti, M, Morari, M, Calo', G, Guerrini, R, Beani, L, Bianchi, C
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572081/
https://ncbi.nlm.nih.gov/pubmed/10807682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703321
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