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Inhibition of cellular responses to insulin in a rat liver cell line. A role for PKC in insulin resistance
The initial response of liver cells to insulin is mediated through exocytosis of Cl(−) channel-containing vesicles and a subsequent opening of plasma membrane Cl(−) channels. Intracellular accumulation of fatty acids leads to profound defects in metabolism, and is closely associated with insulin res...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1665596/ https://ncbi.nlm.nih.gov/pubmed/15649984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.080333 |
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