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Copper inhibits P2Y(2)-dependent Ca(2+) signaling through the effects on thapsigargin-sensitive Ca(2+) stores in HTC hepatoma cells

Purinergic P2Y(2) G-protein coupled receptors play a key role in the regulation of hepatic Ca(2+) signaling by extracellular ATP. The concentration of copper in serum is about 20 μM. Since copper accumulates in the liver in certain disease states, the purpose of these studies was to assess the effec...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Dolovcak, Svjetlana, Waldrop, Shar L., Fitz, J. Gregory, Kilic, Gordan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2899700/
https://ncbi.nlm.nih.gov/pubmed/20515656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.05.141
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