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Copper inhibits P2Y(2)-dependent Ca(2+) signaling through the effects on thapsigargin-sensitive Ca(2+) stores in HTC hepatoma cells

Purinergic P2Y(2) G-protein coupled receptors play a key role in the regulation of hepatic Ca(2+) signaling by extracellular ATP. The concentration of copper in serum is about 20 μM. Since copper accumulates in the liver in certain disease states, the purpose of these studies was to assess the effec...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dolovcak, Svjetlana, Waldrop, Shar L., Fitz, J. Gregory, Kilic, Gordan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2899700/
https://ncbi.nlm.nih.gov/pubmed/20515656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.05.141
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