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Inhibition of cellular responses to insulin in a rat liver cell line. A role for PKC in insulin resistance

The initial response of liver cells to insulin is mediated through exocytosis of Cl(−) channel-containing vesicles and a subsequent opening of plasma membrane Cl(−) channels. Intracellular accumulation of fatty acids leads to profound defects in metabolism, and is closely associated with insulin res...

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Detaylı Bibliyografya
Asıl Yazarlar: Puljak, Livia, Pagliassotti, Michael J, Wei, Yuren, Qadri, Ishtiaq, Parameswara, Vinay, Esser, Victoria, Fitz, J Gregory, Kilic, Gordan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665596/
https://ncbi.nlm.nih.gov/pubmed/15649984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.080333
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