Vasopressin-stimulated CFTR Cl(−) currents are increased in the renal collecting duct cells of a mouse model of Liddle's syndrome

Liddle's syndrome is a genetic form of hypertension linked to Na(+) retention caused by activating mutations in the COOH terminus of the β or γ subunit of the epithelial sodium channel (ENaC). In this study, we used the short-circuit current (I(sc)) method to investigate the effects of deamino-...

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Autors principals: Chang, Chiz-Tzung, Bens, Marcelle, Hummler, Edith, Boulkroun, Sheerazed, Schild, Laurent, Teulon, Jacques, Rossier, Bernard C, Vandewalle, Alain
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2005
Matèries:
Cell Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665473/
https://ncbi.nlm.nih.gov/pubmed/15513933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.077933
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