Direct selection of a human antibody fragment directed against the tumor T-cell epitope HLA-A1–MAGE-A1 from a nonimmunized phage-Fab library

Antitumor antibodies with the same specificity as cytotoxic T lymphocytes that recognize antigenic peptides encoded by tumor-associated genes and presented by MHC class I molecules would be valuable tools to analyze the antigenicity or target tumor cells in vivo. To obtain a human antibody directed...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Chames, Patrick, Hufton, Simon E., Coulie, Pierre G., Uchanska-Ziegler, Barbara, Hoogenboom, Hennie R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16654/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10884427/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.14.7969
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