Functional and molecular evidence of MaxiK channel β1 subunit decrease with coronary artery ageing in the rat

Large-conductance, voltage- and Ca(2+)-activated K(+) channels (MaxiK, BK) are key regulators of vascular tone. Vascular MaxiK are formed by the pore-forming α subunit and the modulatory β1 subunit, which imprints unique kinetics, Ca(2+)/voltage sensitivities and pharmacology to the channel. As age...

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Main Authors: Nishimaru, Kazuhide, Eghbali, Mansoureh, Lu, Rong, Marijic, Jure, Stefani, Enrico, Toro, Ligia
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2004
主題:
Research Papers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665167/
https://ncbi.nlm.nih.gov/pubmed/15272033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.068676
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