Thromboxane A2 receptor and MaxiK-channel intimate interaction supports channel trans-inhibition independent of G-protein activation

Large conductance voltage- and calcium-activated potassium channels (MaxiK, BK(Ca)) are well known for sustaining cerebral and coronary arterial tone and for their linkage to vasodilator β-adrenergic receptors. However, how MaxiK channels are linked to counterbalancing vasoconstrictor receptors is u...

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Bibliographic Details
Main Authors: Li, Min, Tanaka, Yoshio, Alioua, Abderrahmane, Wu, Yong, Lu, Rong, Kundu, Pallob, Sanchez-Pastor, Enrique, Marijic, Jure, Stefani, Enrico, Toro, Ligia
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973862/
https://ncbi.nlm.nih.gov/pubmed/20959415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002685107
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