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Functional and molecular evidence of MaxiK channel β1 subunit decrease with coronary artery ageing in the rat
Large-conductance, voltage- and Ca(2+)-activated K(+) channels (MaxiK, BK) are key regulators of vascular tone. Vascular MaxiK are formed by the pore-forming α subunit and the modulatory β1 subunit, which imprints unique kinetics, Ca(2+)/voltage sensitivities and pharmacology to the channel. As age...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1665167/ https://ncbi.nlm.nih.gov/pubmed/15272033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.068676 |
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