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Activation of single heteromeric GABA(A) receptor ion channels by full and partial agonists

The linkage between agonist binding and the activation of a GABA(A) receptor ion channel is yet to be resolved. This aspect was examined on human recombinant α1β2γ2S GABA(A) receptors expressed in human embryonic kidney cells using the following series of receptor agonists: GABA, isoguvacine, 4,5,6,...

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Detalhes bibliográficos
Main Authors: Mortensen, Martin, Kristiansen, Uffe, Ebert, Bjarke, Frølund, Bente, Krogsgaard-Larsen, Povl, Smart, Trevor G
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665090/
https://ncbi.nlm.nih.gov/pubmed/14990676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.054734
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