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Effects of GABA(A) receptor partial agonists in primary cultures of cerebellar granule neurons and cerebral cortical neurons reflect different receptor subunit compositions

1. Based on an unexpected high maximum response to piperidine-4-sulphonic acid (P4S) at human α1α6β2γ2 GABA(A) receptors expressed in Xenopus oocytes attempts to correlate this finding with the pharmacological profile of P4S and other GABA(A) receptor ligands in neuronal cultures from rat cerebellar...

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Autors principals: Hansen, Suzanne L, Ebert, Bjarke, Fjalland, Bjarne, Kristiansen, Uffe
Format: Artigo
Idioma:Inglês
Publicat: 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572819/
https://ncbi.nlm.nih.gov/pubmed/11399671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704121
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