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Neuroactive steroids have multiple actions to potentiate GABA(A) receptors

The effects of neuroactive steroids on the function of GABA(A) receptors were studied using cell-attached records of single channel activity recorded from HEK293 cells transfected with α1 β2 γ2L subunits. Activity was elicited with a half-maximal (50 μm) concentration of GABA. Two steroids were stud...

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Autors principals: Akk, Gustav, Bracamontes, John R, Covey, Douglas F, Evers, Alex, Dao, Tim, Steinbach, Joe Henry
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664905/
https://ncbi.nlm.nih.gov/pubmed/15146041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.066571
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