Intracellular Na(+) inhibits voltage-dependent N-type Ca(2+) channels by a G protein βγ subunit-dependent mechanism

N-type voltage-dependent Ca(2+) channels (N-VDCCs) play important roles in neurotransmitter release and certain postsynaptic phenomena. These channels are modulated by a number of intracellular factors, notably by Gβγ subunits of G proteins, which inhibit N-VDCCs in a voltage-dependent (VD) manner....

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Detalhes bibliográficos
Main Authors: Blumenstein, Yakov, Maximyuk, Olexandr P, Lozovaya, Natalia, Yatsenko, Natalia M, Kanevsky, Nataly, Krishtal, Oleg, Dascal, Nathan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664899/
https://ncbi.nlm.nih.gov/pubmed/14742725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.056168
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