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Sequestration of G-Protein βγ Subunits by Different G-Protein α Subunits Blocks Voltage-Dependent Modulation of Ca(2+)Channels in Rat Sympathetic Neurons
The membrane-delimited and voltage-dependent inhibition of N-type Ca(2+) channels is mediated by Gβγ subunits. Previously, exogenous excess GDP-bound Gα(oA) has been shown to dramatically attenuate the norepinephrine (NE)-mediated Ca(2+) current inhibition by sequestration of Gβγ subunits in rat sup...
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| Udgivet i: | J Neurosci |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6782646/ https://ncbi.nlm.nih.gov/pubmed/10366609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-12-04755.1999 |
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