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Two modes of polyamine block regulating the cardiac inward rectifier K(+) current I(K1) as revealed by a study of the Kir2.1 channel expressed in a human cell line
The strong inward rectifier K(+) current, I(K1), shows significant outward current amplitude in the voltage range near the reversal potential and thereby causes rapid repolarization at the final phase of cardiac action potentials. However, the mechanism that generates the outward I(K1) is not well u...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1664885/ https://ncbi.nlm.nih.gov/pubmed/14724206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.055434 |
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