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West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H
The complement system, by virtue of its dual effector and priming functions, is a major host defense against pathogens. Flavivirus nonstructural protein (NS)-1 has been speculated to have immune evasion activity, because it is a secreted glycoprotein, binds back to cell surfaces, and accumulates to...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1664712/ https://ncbi.nlm.nih.gov/pubmed/17132743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605668103 |
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