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Stochastic models of receptor oligomerization by bivalent ligand
In this paper, we develop stochastic models of receptor binding by a bivalent ligand. A detailed kinetic study allows us to analyse the role of cross-linking in cell activation by receptor oligomerization. We show how oligomer formation could act to buffer intracellular signalling against stochastic...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1664659/ https://ncbi.nlm.nih.gov/pubmed/16849251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2006.0116 |
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