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Stochastic models of receptor oligomerization by bivalent ligand

In this paper, we develop stochastic models of receptor binding by a bivalent ligand. A detailed kinetic study allows us to analyse the role of cross-linking in cell activation by receptor oligomerization. We show how oligomer formation could act to buffer intracellular signalling against stochastic...

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Autors principals: Alarcón, Tomás, Page, Karen M
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664659/
https://ncbi.nlm.nih.gov/pubmed/16849251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2006.0116
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