Anti-nerve growth factor Ab abrogates macrophage-mediated HIV-1 infection and depletion of CD4(+) T lymphocytes in hu-SCID mice

Infection by HIV-1 causes persistent, long-term high virus production in macrophages. Major evidence, both in humans and in primate models, shows the crucial role of macrophages in sustaining virus production and in mediating a cytopathic effect on bystander CD4(+) T lymphocytes and neuronal cells....

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Autores principales: Garaci, Enrico, Aquaro, Stefano, Lapenta, Caterina, Amendola, Alessandra, Spada, Massimo, Covaceuszach, Sonia, Perno, Carlo-Federico, Belardelli, Filippo
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2003
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC166415/
https://ncbi.nlm.nih.gov/pubmed/12853577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1332627100
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