Potent Immune Response against HIV-1 and Protection from Virus Challenge in hu-PBL-SCID Mice Immunized with Inactivated Virus-pulsed Dendritic Cells Generated in the Presence of IFN-α

A major challenge of AIDS research is the development of therapeutic vaccine strategies capable of inducing the humoral and cellular arms of the immune responses against HIV-1. In this work, we evaluated the capability of DCs pulsed with aldrithiol-2–inactivated HIV-1 in inducing a protective antivi...

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Detalhes bibliográficos
Main Authors: Lapenta, Caterina, Santini, Stefano M., Logozzi, Mariantonia, Spada, Massimo, Andreotti, Mauro, Di Pucchio, Tiziana, Parlato, Stefania, Belardelli, Filippo
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194078/
https://ncbi.nlm.nih.gov/pubmed/12874266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021924
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