Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human β-defensin 3

Human defensins form a family of small, cationic, and Cys-rich antimicrobial proteins that play important roles in innate immunity against invading microbes. They also function as effective immune modulators in adaptive immunity by selectively chemoattracting T lymphocytes and immature dendritic cel...

Full description

Saved in:
Bibliographic Details
Main Authors: Wu, Zhibin, Hoover, David M., Yang, De, Boulègue, Cyril, Santamaria, Fanny, Oppenheim, Joost J., Lubkowski, Jacek, Lu, Wuyuan
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC166407/
https://ncbi.nlm.nih.gov/pubmed/12840147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1533186100
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items