Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human β-defensin 3

Human defensins form a family of small, cationic, and Cys-rich antimicrobial proteins that play important roles in innate immunity against invading microbes. They also function as effective immune modulators in adaptive immunity by selectively chemoattracting T lymphocytes and immature dendritic cel...

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Detalhes bibliográficos
Main Authors: Wu, Zhibin, Hoover, David M., Yang, De, Boulègue, Cyril, Santamaria, Fanny, Oppenheim, Joost J., Lubkowski, Jacek, Lu, Wuyuan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC166407/
https://ncbi.nlm.nih.gov/pubmed/12840147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1533186100
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