Modeling the fission yeast cell cycle: Quantized cycle times in wee1(−) cdc25Δ mutant cells
A detailed mathematical model for the fission yeast mitotic cycle is developed based on positive and negative feedback loops by which Cdc13/Cdc2 kinase activates and inactivates itself. Positive feedbacks are created by Cdc13/Cdc2-dependent phosphorylation of specific substrates: inactivating its ne...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16636/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10884416/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.14.7865 |
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