A distinct nuclear localization signal in the N terminus of Smad 3 determines its ligand-induced nuclear translocation
Smad proteins are intracellular mediators of transforming growth factor β (TGF-β) and related cytokines and undergo ligand-induced nuclear translocation. Here we describe the identification of a nuclear localization signal (NLS) in the N-terminal region of Smad 3, the major Smad protein involved in...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16634/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10884415/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.14.7853 |
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