A distinct nuclear localization signal in the N terminus of Smad 3 determines its ligand-induced nuclear translocation

Smad proteins are intracellular mediators of transforming growth factor β (TGF-β) and related cytokines and undergo ligand-induced nuclear translocation. Here we describe the identification of a nuclear localization signal (NLS) in the N-terminal region of Smad 3, the major Smad protein involved in...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Xiao, Zhan, Liu, Xuedong, Henis, Yoav I., Lodish, Harvey F.
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16634/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10884415/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.14.7853
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