Llwytho...

A Novel Mechanism for Wnt Activation of Canonical Signaling through the LRP6 Receptor

LDL receptor-related protein 6 (LRP6) is a Wnt coreceptor in the canonical signaling pathway, which plays essential roles in embryonic development. We demonstrate here that wild-type LRP6 forms an inactive dimer through interactions mediated by epidermal growth factor repeat regions within the extra...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liu, Guizhong, Bafico, Anna, Harris, Violaine K., Aaronson, Stuart A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC166321/
https://ncbi.nlm.nih.gov/pubmed/12897152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.16.5825-5835.2003
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!