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The Mechanism of Endogenous Receptor Activation Functionally Distinguishes Prototype Canonical and Noncanonical Wnts
Wnt glycoproteins are developmentally essential signaling molecules, and lesions afflicting Wnt pathways play important roles in human diseases. Some Wnts signal to the canonical pathway by stabilizing β-catenin, while others lack this activity. Frizzled serpentine receptors mediate distinct signali...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1084300/ https://ncbi.nlm.nih.gov/pubmed/15831454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.9.3475-3482.2005 |
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