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The Mechanism of Endogenous Receptor Activation Functionally Distinguishes Prototype Canonical and Noncanonical Wnts
Wnt glycoproteins are developmentally essential signaling molecules, and lesions afflicting Wnt pathways play important roles in human diseases. Some Wnts signal to the canonical pathway by stabilizing β-catenin, while others lack this activity. Frizzled serpentine receptors mediate distinct signali...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1084300/ https://ncbi.nlm.nih.gov/pubmed/15831454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.9.3475-3482.2005 |
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