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Critical role of IL-10 in the induction of low zone tolerance to contact allergens

The development and mechanisms of tolerance to allergens are poorly understood. Using the murine low zone tolerance (LZT) model, where contact hypersensitivity (CHS) is prevented by repeated topical low-dose applications of contact allergens, we show that LZT induction is IL-10 dependent. IL-10 is r...

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Detalhes bibliográficos
Main Authors: Maurer, Marcus, Seidel-Guyenot, Wolfgang, Metz, Martin, Knop, Juergen, Steinbrink, Kerstin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC166297/
https://ncbi.nlm.nih.gov/pubmed/12865418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318106
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