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Critical role of IL-10 in the induction of low zone tolerance to contact allergens
The development and mechanisms of tolerance to allergens are poorly understood. Using the murine low zone tolerance (LZT) model, where contact hypersensitivity (CHS) is prevented by repeated topical low-dose applications of contact allergens, we show that LZT induction is IL-10 dependent. IL-10 is r...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC166297/ https://ncbi.nlm.nih.gov/pubmed/12865418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318106 |
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