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The substrate specificity-determining amino acid code of 4-coumarate:CoA ligase
To reveal the structural principles determining substrate specificity of 4-coumarate:CoA ligase (4CL), the crystal structure of the phenylalanine activation domain of gramicidin S synthetase was used as a template for homology modeling. According to our model, 12 amino acid residues lining the Arabi...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC166275/ https://ncbi.nlm.nih.gov/pubmed/12819348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1430550100 |
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