The substrate specificity-determining amino acid code of 4-coumarate:CoA ligase
To reveal the structural principles determining substrate specificity of 4-coumarate:CoA ligase (4CL), the crystal structure of the phenylalanine activation domain of gramicidin S synthetase was used as a template for homology modeling. According to our model, 12 amino acid residues lining the Arabi...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166275/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12819348/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1430550100 |
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