The substrate specificity-determining amino acid code of 4-coumarate:CoA ligase

To reveal the structural principles determining substrate specificity of 4-coumarate:CoA ligase (4CL), the crystal structure of the phenylalanine activation domain of gramicidin S synthetase was used as a template for homology modeling. According to our model, 12 amino acid residues lining the Arabi...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Schneider, Katja, Hövel, Klaus, Witzel, Kilian, Hamberger, Björn, Schomburg, Dietmar, Kombrink, Erich, Stuible, Hans-Peter
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2003
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166275/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12819348/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1430550100
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