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Human topoisomerase I promotes HIV-1 proviral DNA synthesis: Implications for the species specificity and cellular tropism of HIV-1 infection

Although HIV type 1 (HIV-1) cannot efficiently replicate in simian cells, the mechanism(s) involved in the restriction of virus tropism remain unclear. To investigate this, we have focused on the identification of human cellular factors that can influence the infectivity of HIV-1 derived from Africa...

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Detalhes bibliográficos
Main Authors: Shoya, Yuko, Tokunaga, Kenzo, Sawa, Hirofumi, Maeda, Masae, Ueno, Tomonori, Yoshikawa, Tomoki, Hasegawa, Hideki, Sata, Tetsutaro, Kurata, Takeshi, Hall, William W., Cullen, Bryan R., Takahashi, Hidehiro
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC166248/
https://ncbi.nlm.nih.gov/pubmed/12829794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1430827100
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