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The Alpha/Beta Interferon Response Controls Tissue Tropism and Pathogenicity of Poliovirus
Poliovirus selectively replicates in neurons in the spinal cord and brainstem, although poliovirus receptor (PVR) expression is observed in both the target and nontarget tissues in humans and transgenic mice expressing human PVR (PVR-transgenic mice). We assessed the role of alpha/beta interferon (I...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1061561/ https://ncbi.nlm.nih.gov/pubmed/15767446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.7.4460-4469.2005 |
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