The Alpha/Beta Interferon Response Controls Tissue Tropism and Pathogenicity of Poliovirus

Poliovirus selectively replicates in neurons in the spinal cord and brainstem, although poliovirus receptor (PVR) expression is observed in both the target and nontarget tissues in humans and transgenic mice expressing human PVR (PVR-transgenic mice). We assessed the role of alpha/beta interferon (I...

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Détails bibliographiques
Auteurs principaux: Ida-Hosonuma, Miki, Iwasaki, Takuya, Yoshikawa, Tomoki, Nagata, Noriyo, Sato, Yuko, Sata, Tetsutaro, Yoneyama, Mitsutoshi, Fujita, Takashi, Taya, Choji, Yonekawa, Hiromichi, Koike, Satoshi
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061561/
https://ncbi.nlm.nih.gov/pubmed/15767446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.7.4460-4469.2005
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