The Alpha/Beta Interferon Response Controls Tissue Tropism and Pathogenicity of Poliovirus

Poliovirus selectively replicates in neurons in the spinal cord and brainstem, although poliovirus receptor (PVR) expression is observed in both the target and nontarget tissues in humans and transgenic mice expressing human PVR (PVR-transgenic mice). We assessed the role of alpha/beta interferon (I...

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Detalhes bibliográficos
Main Authors: Ida-Hosonuma, Miki, Iwasaki, Takuya, Yoshikawa, Tomoki, Nagata, Noriyo, Sato, Yuko, Sata, Tetsutaro, Yoneyama, Mitsutoshi, Fujita, Takashi, Taya, Choji, Yonekawa, Hiromichi, Koike, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061561/
https://ncbi.nlm.nih.gov/pubmed/15767446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.7.4460-4469.2005
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