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The RNA–protein complex: Direct probing of the interfacial recognition dynamics and its correlation with biological functions

The N protein from bacteriophage λ is a key regulator of transcription antitermination. It specifically recognizes a nascent mRNA stem loop termed boxB, enabling RNA polymerase to read through downstream terminators processively. The stacking interaction between Trp-18 of WT N protein and A7 of boxB...

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Main Authors: Xia, Tianbing, Becker, Hans-Christian, Wan, Chaozhi, Frankel, Adam, Roberts, Richard W., Zewail, Ahmed H.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC166192/
https://ncbi.nlm.nih.gov/pubmed/12815093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1433099100
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