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RNA–protein recognition: Single-residue ultrafast dynamical control of structural specificity and function
The transcription antiterminator N protein from bacteriophage λ uses its arginine-rich motif to specifically bind a stem-loop RNA hairpin (boxB) as a bent α-helix. A single stacking interaction between a tryptophan (Trp-18) and an adenosine (A7) in the RNA loop is robust and necessary for antitermin...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201610/ https://ncbi.nlm.nih.gov/pubmed/16129822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506181102 |
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