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SPARC-Induced Migration of Glioblastoma Cell Lines via uPA-uPAR Signaling and Activation of Small GTPase RhoA

Secreted protein acidic and rich in cysteine (SPARC) is highly expressed in human gliomas where it promotes invasion and delays tumor growth, both in vitro and in vivo. SPARC, which interacts at the cell surface, has an impact on intracellular signaling and downstream gene expression changes, which...

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Bibliografske podrobnosti
Main Authors: Kunigal, Sateesh, Gondi, Christopher, Gujrati, Meena, Lakka, Sajani S., Dinh, Dzung H., Olivero, William C., Rao, Jasti S.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1661847/
https://ncbi.nlm.nih.gov/pubmed/17088972
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