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A simple dependence between protein evolution rate and the number of protein-protein interactions

BACKGROUND: It has been shown for an evolutionarily distant genomic comparison that the number of protein-protein interactions a protein has correlates negatively with their rates of evolution. However, the generality of this observation has recently been challenged. Here we examine the problem usin...

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Detalhes bibliográficos
Main Authors: Fraser, Hunter B, Wall, Dennis P, Hirsh, Aaron E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC166126/
https://ncbi.nlm.nih.gov/pubmed/12769820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-3-11
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