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Evolutionary rate depends on number of protein-protein interactions independently of gene expression level

BACKGROUND: Whether or not a protein's number of physical interactions with other proteins plays a role in determining its rate of evolution has been a contentious issue. A recent analysis suggested that the observed correlation between number of interactions and evolutionary rate may be due to...

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Detalhes bibliográficos
Main Authors: Fraser, Hunter B, Hirsh, Aaron E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC420460/
https://ncbi.nlm.nih.gov/pubmed/15165289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-4-13
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