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No simple dependence between protein evolution rate and the number of protein-protein interactions: only the most prolific interactors tend to evolve slowly
BACKGROUND: It has been suggested that rates of protein evolution are influenced, to a great extent, by the proportion of amino acid residues that are directly involved in protein function. In agreement with this hypothesis, recent work has shown a negative correlation between evolutionary rates and...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140311/ https://ncbi.nlm.nih.gov/pubmed/12515583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-3-1 |
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