A novel copper complex induces ROS generation in doxorubicin resistant Ehrlich ascitis carcinoma cells and increases activity of antioxidant enzymes in vital organs in vivo

BACKGROUND: In search of a suitable GSH-depleting agent, a novel copper complex viz., copper N-(2-hydroxyacetophenone) glycinate (CuNG) has been synthesized, which was initially found to be a potential resistance modifying agent and later found to be an immunomodulator in mice model in different dos...

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Détails bibliographiques
Auteurs principaux: Mookerjee, Ananda, Basu, Jayati Mookerjee, Majumder, Surajit, Chatterjee, Shilpak, Panda, Gouri S, Dutta, Pranabananda, Pal, Smarajit, Mukherjee, Pratima, Efferth, Thomas, Roy, Syamal, Choudhuri, Soumitra K
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2006
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1660546/
https://ncbi.nlm.nih.gov/pubmed/17107616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-267
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