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Artesunate Induces ROS-Mediated Apoptosis in Doxorubicin-Resistant T Leukemia Cells

BACKGROUND: A major obstacle for successful cancer treatment often is the development of drug resistance in cancer cells during chemotherapy. Therefore, there is an urgent need for novel drugs with improved efficacy against tumor cells and with less toxicity on normal cells. Artesunate (ART), a powe...

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Detalhes bibliográficos
Main Authors: Efferth, Thomas, Giaisi, Marco, Merling, Annette, Krammer, Peter H., Li-Weber, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933253/
https://ncbi.nlm.nih.gov/pubmed/17668070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000693
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