Both Interleukin-4 (IL-4) and IL-4 Receptor α Signaling Contribute to the Development of Hepatic Granulomas with Optimal Antileishmanial Activity

The roles of interleukin-4 (IL-4) and IL-13 in the regulation of immunity to Leishmania donovani infection are still poorly understood. Here we show that the increased parasite load observed in IL-4(−/−) and IL-4 receptor α(−/−) mice correlates with retarded granuloma maturation and antileishmanial...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Stäger, Simona, Alexander, James, Carter, K. Christine, Brombacher, Frank, Kaye, Paul M.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2003
Fag:	Fungal and Parasitic Infections
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166035/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12874364/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.8.4804-4807.2003
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