Both Interleukin-4 (IL-4) and IL-4 Receptor α Signaling Contribute to the Development of Hepatic Granulomas with Optimal Antileishmanial Activity
The roles of interleukin-4 (IL-4) and IL-13 in the regulation of immunity to Leishmania donovani infection are still poorly understood. Here we show that the increased parasite load observed in IL-4(−/−) and IL-4 receptor α(−/−) mice correlates with retarded granuloma maturation and antileishmanial...
Guardat en:
| Publicat a: | Infect Immun |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166035/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12874364/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.8.4804-4807.2003 |
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