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Pseudocomplementary PNAs as selective modifiers of protein activity on duplex DNA: the case of type IIs restriction enzymes

This study evaluates the potential of pseudocomplementary peptide nucleic acids (pcPNAs) for sequence-specific modification of enzyme activity towards double-stranded DNA (dsDNA). To this end, we analyze the ability of pcPNA–dsDNA complexes to site-selectively interfere with the action of four type...

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Udgivet i:Nucleic Acids Res
Principais autores: Protozanova, Ekaterina, Demidov, Vadim V., Nielsen, Peter E., Frank-Kamenetskii, Maxim D.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165965/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12853608/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg450
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