Efficiency of single-nucleotide polymorphism haplotype estimation from pooled DNA
The efficiency of single-nucleotide polymorphism haplotype analysis may be increased by DNA pooling, which can dramatically reduce the number of genotyping assays. We develop a method for obtaining maximum likelihood estimates of haplotype frequencies for different pool sizes, assess the accuracy of...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165857/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12777616/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1237858100 |
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