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BRCA2 cooperates with histone acetyltransferases in androgen receptor-mediated transcription
Germ-line mutations of the BRCA2 tumor suppressor gene greatly increase the risk of developing breast and ovarian cancers. Here, we show that wild-type BRCA2, but not a tumor-specific truncated mutant BRCA2, synergizes with the nuclear receptor coactivator p160 GRIP1 to enhance transcriptional activ...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165853/ https://ncbi.nlm.nih.gov/pubmed/12756300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1132020100 |
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