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The transient receptor potential channel on the yeast vacuole is mechanosensitive

Ca(2+) is released from the vacuole into the yeast cytoplasm on an osmotic upshock, but how this upshock is perceived was unknown. We found the vacuolar channel, Yvc1p, to be mechanosensitive, showing that the Ca(2+) conduit is also the sensing molecule. Although fragile, the yeast vacuole allows li...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Zhou, Xin-Liang, Batiza, Ann F., Loukin, Stephen H., Palmer, Chris P., Kung, Ching, Saimi, Yoshiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165837/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12771382/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1230540100
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